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by Tian, T. et al. Its overexpression induced CTGF up-regulation in GBM at both the mRNA and protein level, and significantly enhanced the activity of CTGF promoter in these tumor cells, while...

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by Pei, C. et al.TGF-β2 and CTGF could induce HLECs epithelial mesenchymal transition and ECM synthesis.Int. J. Ophthalmol. 2013; 6:752-7[See paper]

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by Guo, Y. et al.Department of Nephrology, General Hospital of Jinan Military Jinan, Shangdong, China Interestingly, genistein effectively inhibited PTH-induced α-SMA expression, restored E-cadherin...

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by Liu, S.C. et al.Institute of Biomedical Sciences, National Chung Hsing University, Taichung, TaiwanOur results suggest that CTGF increased IL-6 production in OASFs via the αvβ5 integrin, ASK1,...

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by Fox, J.L. et al.Division of Cancer Pathobiology, Department of Pathology & Laboratory Medicine, Center for Childhood Cancer Research, Children’s Hospital of Philadelphia, USATargeting of TGFβ...

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by Mason, R.M.Renal Section, Department of Medicine, Imperial College London, London, UKFell-Muir lecture: Connective tissue growth factor (CCN2) -- a pernicious and pleiotropic player in the...

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by Zhu, J. et al.Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, USAInhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix...

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by Kiryu, M. et al.Department of Cardio-Angiology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Japan Because this up-regulation was independent of TGF-β and suppressed by...

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by Li, W. et al.Renal Division, Department of Medicine, Shandong Provincial Qianfoshan Hospital, Jinan CityThe findings showed that exendin-4 inhibited the proliferation of HMCs, and upregulated the...

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by Geng, H. et al.Department of Pathology, University of Texas Health Science Center, San Antonio, Texas Treatment with a pharmacological TGF-β type I receptor antagonist suppressed TGF-β signaling,...

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by Nagaraja, T. et al.Department of Pathology, Ohio State University Wexner Medical Center, Columbus, Ohio, United States of AmericaOur studies demonstrate a central role for CTGF expression in...

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by Bartel, F. et al.Institute of Pathology, Martin Luther University Halle-Wittenberg, Halle, Germany Moreover, Cyr61 was found to be preferentially expressed in high-grade serous carcinomas, whereas...

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by Sarközi, R. et al.Department of Internal Medicine IV, Nephrology and Hypertension, Innsbruck Medical University, Innsbruck, Austria Together these results suggest that the inhibitory effect of OSM...

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by Jiang, C.G. et al.Department of Surgical Oncology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, ChinaConnective tissue growth factor is a positive...

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by Yagi, H. et al.Department of Medicine and Biological Science, Gunma University Graduate School of Medicine The plasma CTGF level can be strongly related with cardiac sympathetic nerve activity in...

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by Bauer, S. et al.Department of Internal Medicine I, Regensburg University Hospital, Germany CTGF is not associated with stages of liver cirrhosis defined by CHILD-PUGH or MELD score nor with...

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by Altuntas, C.Z. et al.Urology Institute, Univ. Hospitals Case Medical Center; Dept. of Urology, Case Western Reserve Univ. School of Medicine; 11100 Euclid Ave., Lakeside Bldg.Connective tissue and...

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by Patel, S.K. et al.Department of Medicine, Austin Health, University of Melbourne, Level 7, AustraliaThe CTGF gene -945 G/C polymorphism is not associated with cardiac or kidney complications in...

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by Gu, J. et al.Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University School of medicine, Shanghai, China AngII (1μM) also promoted TGFβ1, TRAF6, CTGF expression and TAK1...

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by Iyer, P. et al.Departments of Ophthalmology andConnective tissue growth factor-mediated upregulation of neuromedin u expression in trabecular meshwork cells and its role in homeostasis of aqueous...

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by Tong, M. et al.Division of Renal Medicine, Guangxin Hospital, Zhejiang Chinese Medical University, Hangzhou, ChinaAGEs can markedly increase the expression of mRNA and protein for FN and CTGF;...

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by Pantou, M.P. et al.Molecular Immunopathology and Histocompatibility Laboratory, Onassis Cardiac Surgery Center, Athens, Greece The CAV patients, who were all receiving everolimus treatment,...

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by Capparelli, C. et al.The Jefferson Stem Cell Biology and Regenerative Medicine Center; Kimmel Cancer Center; Thomas Jefferson University; Philadelphia, PA USA; Departments of Stem Cell Biology...

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by Huang, G. et al.Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, 700 Childrens Drive Columbus, Ohio, 43205 USA, USARegulation of hepatic...

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by Honsawek, S. et al.Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, ThailandPlasma and synovial fluid connective tissue growth factor...

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by Kim, J.S. et al.Specialization Research Center, Hallym University Burn Institute, Hangang Sacred Heart Hospital, Hallym University, South Korea In particular, the combination of LY294002 or PP2...

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by El-Shewy, H.M. et al.Department of Biochemistry and Molecular Genetics, Faculty of Medicine, Riad El-Solh Street, American University of Beirut, Lebanon LDL-induced CTGF expression was pertussis...

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by Rico, M.C. et al.Department of Physiology, Temple University School of Medicine, Philadelphia, PA, 19140, United States TSP1 alone upregulated CTGF/CCN2, an effect mediated via activation of...

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by Guo, Y.S. et al.Department of Nephrology, General Hospital of Jinan Military Command, Jinan, Shandong 250031, ChinaPD98059 inhibited the PTH stimulated expression of CTGF, which strongly suggested...

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by Du, J. et al.Department of Nephrology, First Hospital of China Medical University, 155 North Nanjing Street, Shenyang City, China This study shows that IFN-γ phosphorylates STAT1, suppresses HMC...

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by Dai, H.Y. et al.Institute of Nephrology, Zhongda Hospital, Southeast University School of Medicine, Nanjing 210009, China ILK acted as a downstream kinase of CTGF and high glucose-induced ILK...

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by Chang, J.Z. et al.School of Dentistry, College of Medicine and Department of Dentistry, National Taiwan University Hospital, National Taiwan University, TaiwanThrombin-stimulated connective tissue...

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by Yang, M.H. et al.1] Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan [2] Division of Hematology-Oncology, TaiwanConnective tissue growth factor modulates oral squamous...

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by Wang, J.G. et al.Department of Biochemistry School of Basic Medical Sciences, Wenzhou Medical College, Wenzhou, China CTGF, a member of the C-terminal cystein-rich proteins (CCN) family, was...

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by Cabello-Verrugio, C. et al.Centro de Regulación Celular y Patología (CRCP), Centro de Regeneración y Envejecimiento (CARE), Laboratorio de Diferenciación Celular y Patología, Departamento de...

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by Lai, K.B. et al.The regulatory effect of norepinephrine on connective tissue growth factor (CTGF) and vascular endothelial growth factor (VEGF) expression in cultured cardiac fibroblasts.Int. J....

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by Gerritsen, K.G. et al.Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Nephrology and Hypertension, Netherlands In patients with end-stage kidney...

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by Ellina, O. et al.Extracellular matrix-associated (GAGs, CTGF), angiogenic (VEGF) and inflammatory factors (MCP-1, CD40, IFN-γ) in type 1 diabetes mellitus nephropathy.Clin. Chem. Lab. Med. 2012;...

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by Gambichler, T. et al.Department of Dermatology Department of Medicine I, Ruhr-University Bochum, Bochum, GermanyDifferential expression of connective tissue growth factor and extracellular matrix...

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by Xiang, Z.L. et al.Department of Radiation Oncology, Zhongshan Hospital, Fudan University, 136 Yi Xue Yuan Road, China High intratumoral CTGF expression was associated with vascular invasion (P =...

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by Maybin, J.A. et al.MRC Centre for Reproductive Health, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UKThe presence and regulation of connective tissue...

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by Van Geest, R.J. et al.Medical Retina Unit and Ocular Angiogenesis Group, Department of Ophthalmology, Academic Medical Center, Room A2-122, The Netherlands; The CTGF/VEGF ratio was the strongest...

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by Urtasun, R. et al.Division of Hepatology and Gene Therapy, CIMA, University of Navarra, Pamplona, Spain Expression of CTGF can be stimulated through the EGFR-signaling system in HCC cells in a...

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by Walter, R. et al.Department of Internal Medicine I, University Hospital of Regensburg, Germany CTGF and TGFβ mRNA levels were increased in human non-fibrotic non-alcoholic steatohepatitis (NASH),...

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by Haafiz, A. et al.Hepatology and Liver Transplantation, Division of Pediatric Gastroenterology, Hepatology and NutritionSimilar analysis for alanine aminotransferase, TB, and GGT combination...

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by Zhao, H. et al.Compared with the control group, significantly increased (p < 0.01) levels of CTGF and TGF-β1 protein were observed in the anastomotic stenosis (AS) group, and levels of the two...

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by Ahmad, A. et al.Investigating the association between polymorphisms in connective tissue growth factor and susceptibility to colon carcinoma.Mol. Med. Rep. 2015; 4:2493-503[See paper]

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by Zhang, P. et al.Increased Expression of Connective Tissue Growth Factor (CTGF) in Multiple Organs After Exposure of Non-Human Primates (NHP) to Lethal Doses of Radiation.Health. Phys. 2015;...

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by Kuespert, S. et al. Latrunculin A reduced expression of CTGF by about 50% compared to untreated HTM cells, whereas endothelin-1, IGF-1, angiotensin-II, heat shock and oxidative stress led to a...

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by Tsai, C.C. et al. Importantly, pre-incubation with antioxidants including N-acetylcysteine (NAC) and vitamin C, respectively, resulted in significant attenuation of the induction of CTGF in GO...

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